Lead Levels Associated with Nutritional Deficiencies

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Lead Levels Associated with Nutritional Deficiencies

Low-level lead exposure has been associated with elevated blood pressure, renal dysfunction and anemia in adults, and cognitive and behavioral deficits in children.

Mounting evidence suggests that vitamins and minerals can interact with lead in a variety of physiological processes, including intestinal absorption, retention and secretion, and mobilization and distribution between osseous and nonos-seous tissues.

The potential relationship between nutritional factors and lead accumulation was examined in a study of 747 men aged 49-93. Lower dietary intake of vitamin C and iron increased lead levels in the blood, while low vitamin D intake was associated with increased levels of lead in the bone.

Advances in laboratory analysis and epidemiology in the past decade have demonstrated that even very low-level exposure to lead can produce toxic effects on the body. Nutritional interventions emphasizing adequate intake of vitamin C, vitamin D, and iron may help reduce the impact of lead exposure.

Cheng Y, Willett WC, et al. Relation of nutrition to bone lead and blood lead levels in middle-aged to elderly men. American Journal of Epidemiology, 1998;147(12), pp1162-74.